Welcome

CMC Solutions bvba is a chemistry-based research company specialized in the design and synthesis and development of organic compounds for the pharmaceutical, agrochemical, and biotechnology industries. CMC Solutions is a privately owned and family financed company.

We see ourselves as a custom research organisation with a broad field within synthetic organic chemistry.

We are a supplier for non-commercially available starting materials, advanced intermediates, library synthesis and custom synthesis for novel chemotypes. We also do trouble-shooting for difficult synthesis and libraries.

We do classical process development for any type of chemistry as well as in new reactor technologies for continuous processes including synthesis of difficult to obtain compounds. The reactor either fixed bed microreactor or tube reactor is adopted to the chemical process for the best fit.

We design any type of continuous reactor system needed for all types of reactions including hazardous chemistry as for instance diazo chemistry or fluorinations as well as conditions with high temperature and high pressure including the use of reactions not useful for batch reactors.

We also do development of various solid types of catalytic systems for batch or continuous mode including novel nanoparticle catalytic system on silica. We design and produce the catalyst in-house in the quality needed for the process. All catalysts can be produced on large scale and recycled when needed.

Recently we have made a collaboration agreement with Neuland Laboratories Limited in India for GMP production.

Testimonials

"Working with CMC Solutions on the preparation of tool compounds for medicinal chemistry was a smooth and successful experience. Despite unforeseen synthetic challenges Ulf Tilstam was able to rapidly come up with an optimized route. The desired compounds were delivered in high quality and ordered amounts. Regular and detailed updates on the current status of the synthesis were given. Overall the project was handled in a highly professional manner."

Dr. Hilmar Weinmann
Director
Bayer Pharma AG

"CMC Solutions delivered on our proposal. I was impress with the knowledge and command of the organic chemistry literature CMC displayed. Before engaging in any wet chemistry, a thorough plan which was based on the literature background information was presented. Execution of our project was engaging with weekly updates. In the end, a complete data set was provided. As a result, we obtained an excellent understanding of the reaction along with several options for future development."

David Mitchell, PhD
Research Advisor
Eli Lilly and Company